Balancing mood is a delicate biological process that involves both the formation and breakdown of neurotransmitters. L-Methylfolate needs assistance from other nutrients in both of these processes. Due to less than ideal diets or digestive functions, these cofactors may be in short supply. To give L-methylfolate the help it needs, we have provided it in a formula with its top cofactors, B-6 and B-12. In addition, we’ve included magnesium which assists the COMT (catechol-O-methyltransferase) enzyme in the breakdown of certain neurotransmitters like dopamine and epinephrine.